An Electrophysiological Analysis of Chronic Ethanol Effects on Synaptic Distribution and Function in Rat Hippocampus

Abstract:

This is a PhD thesis that investigated how chronic ethanol consumption by rats, followed by 2 months of abstinence,affected the functional connectivity of several pathways in the hippocampus. The techniques entailed field potential electrophysiology in anesthetized animals, which was used to investigate basal synaptic transmission, short-term plasticity and long-term potentiaton. Connectivity patterns were assessed using current source density analyses of depth profile data. The findings have been published as 4 papers in 1981, 1982, 1984.

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