Antibody Engineering

This book will help researchers understand and develop designer antibodies. It is a practical `how-to' overview using state-of-the-art technologies, of antibody engineering for the production of recombinant human or mouse monoclonal antibodies. Subjects such as antibody structure relevant to antibody engineering, plant and mammalian expression vectors and hosts, recombinatorial DNA libraries, PCR cloning of single cells, engineering of affinity and biological effector functions, are thoroughly dealt with by some of the leading experts in each field.