bokomslag Aquaporins in Health and Disease
Kropp & själ

Aquaporins in Health and Disease

Graca Soveral Soren Nielsen Angela Casini

Inbunden

3719:-

Funktionen begränsas av dina webbläsarinställningar (t.ex. privat läge).

Tillfälligt slut online – klicka på "Bevaka" för att få ett mejl så fort varan går att köpa igen.

Andra format:

  • 356 sidor
  • 2015
Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed the importance of aquaporins in mammalian physiology and pathophysiology as well as plant and microbial biology. The studies have also shown aquaporins as potential drug targets and targets for improving crop properties. Written by an international group of contributors at the forefront of the field, Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery presents the latest research advances in aquaporins and other major intrinsic protein (MIP) channels. The first section of the book describes the general concepts of aquaporin channel function, genomic research, structure-function analysis of aquaporins and glycerol facilitators, and regulation by gating and trafficking, including yeast aquaporin regulation and function. The second section discusses the physiological and pathophysiological roles of aquaporins in humans and microbes. The final section covers the development of inhibitors of aquaporin function. The books epilogue offers future perspectives and directions, mainly in the area of aquaporin-based diagnostics and therapeutics. Stimulating future research on this important protein family, this book facilitates a paradigm shift in the understanding and roles of aquaporin membrane proteins in all biological settings. It encourages scientists to develop novel approaches for the treatment of human diseases based on aquaporin function or dysfunction.
  • Författare: Graca Soveral, Soren Nielsen, Angela Casini
  • Format: Inbunden
  • ISBN: 9781498707831
  • Språk: Engelska
  • Antal sidor: 356
  • Utgivningsdatum: 2015-12-24
  • Förlag: CRC Press Inc