bokomslag Biogenic Amine Receptors
Psykologi & pedagogik

Biogenic Amine Receptors

Leslie Iversen

Pocket

739:-

Funktionen begränsas av dina webbläsarinställningar (t.ex. privat läge).

Uppskattad leveranstid 7-12 arbetsdagar

Fri frakt för medlemmar vid köp för minst 249:-

  • 307 sidor
  • 2012
1 Amine Receptors in CNS. I. Norepinephrine.- 1. Introduction.- 2. Localizing Norepinephrine-Containing Synapses.- 3. Effects of Norepinephrine on Central Neurons.- 3.1. Overview of Microiontophoretic Studies.- 3.2. Identification of Test Neurons.- 4. Action of Norepinephrine on Defined Postsynaptic Neurons.- 4.1. The Noradrenergic Projection to Rat Cerebellar Purkinje Cells.- 4.2. Characterization of the Purkinje Cell Adrenergic Receptor.- 4.3. Activation of the Adrenergic Pathway.- 5. The Noradrenergic Projection to Rat Hippocampal Pyramidal Cells and Other Brain Stem Areas.- 6. Cyclic 3?,5?-Adenosine Monophosphate as a Mediator of Norepinephrine Action in the Central Nervous System.- 6.1. Interpreting the Failures to Confirm Neuronal Depression by Cyclic AMP.- 6.2. Actions of Calcium.- 7. Conclusions.- 8. References.- 2 Amine Receptors in CNS. II. Dopamine.- 1. Introduction.- 2. Localization and Function of Dopamine.- 2.1. Cerebral Cortex.- 2.2. Retina.- 2.3. Hypothalamus.- 2.4. Basal Ganglia.- 3. Synthesis and Degradation of Striatal Dopamine.- 4. Stimulus-Evoked Release of Dopamine in Striatum.- 5. Dopamine Receptor Activation: Effects of Dopamine on Striatal Neurons.- 6. Pharmacological Characterization of Presumed Dopaminergic Neurons.- 7. Presynaptic vs. Postsynaptic Dopamine Receptors.- 8. Behavioral Studies.- 8.1. Turning Behavior.- 8.2. Stereotyped Behavior.- 8.3. Compulsive Gnawing Syndrome.- 9. Structural Conformations.- 9.1. Dopamine.- 9.2. Dopamine Agonists.- 9.3. Dopamine Antagonists.- 10. Dopamine Receptor: Adenylate Cyclase.- 11. Conclusion.- 12. References.- 3 Amine Receptors in CNS. III. 5-Hydroxytryptamine in Brain.- 1. Introduction.- 2. Experimental Studies on 5-HT Receptors.- 2.1. Physiological Effects of 5-HT on Brain Neurons.- 2.2. Studies on Putative 5-HT Agonists and Antagonists in Brain.- 2.3. Studies on in Vitro Binding of 5-HT and LSD: Possible Relationship to 5-HT Receptors.- 3. Conclusions.- 4. References.- 4 Acetylcholine Receptors in Vertebrate CNS.- 1. Introduction.- 2. In Vivo Effects of ACh and Agonists on CNS.- 2.1. Gross Applications and Recording.- 2.2. Effects of Microapplications.- 2.3. Distribution of Different Kinds of ACh Receptors.- 2.4. ACh Receptors on Other Tissue Components.- 3. In Vitro Effects of ACh and Agonists on CNS.- 3.1. ACh Responses of Neuroblastoma Cells.- 3.2. Isolation of Central ACh Receptors.- 3.3. Role of Guanosine Derivatives in ACh Response.- 4. Significance of ACh Receptors.- 5. Evidence for Central Cholinergic Neurotransmission and Its Functional Significance.- 5.1. Fast Excitation.- 5.2. Slow Excitation.- 5.3. Inhibition.- 6. References.- 5 Receptor Feedback and Dopamine Turnover in CNS.- 1. Introduction.- 1.1. Brain Dopamine.- 1.2. Dopamine Receptors.- 2. Dopamine as a Transmitter Substance in CNS.- 2.1. Chemical Identification.- 2.2. Distribution of Dopamine Neurons.- 3. T ransmitter Metabolism in Brain Dopamine Neurons.- 3.1. Synthesis.- 3.2. Dopamine Metabolism.- 3.3. Dopamine Turnover.- 4. Effect of Dopamine Receptor Blocking Drugs on Transmitter Turnover.- 4.1. Neuroleptics.- 4.2. Chlorpromazine Metabolites.- 5. Effect of Dopamine Receptor Stimulating Drugs on Transmitter Turnover.- 5.1. Apomorphine and Related Compounds.- 5.2. Piribedil.- 6. Relation Between Drug Effects on Dopamine Turnover Regulation in Vivo and Dopamine-Stimulated Adenylate Cyclase Activity in Vitro.- 7. Evidence for Receptor-Mediated Control of Brain Dopamine Turnover in Man.- 8. References.- 6 Basic Mechanisms and Local Feedback Control of Secretion of Adrenergic and Cholinergic Neurotransmitters.- 1. Introduction.- 2. Secretion of Adrenergic and Cholinergic Neurotransmitters.- 2.1. Basic Mechanisms.- 2.2. Conflicting Current Concepts of Basic Mechanisms in Neurotransmitter Secretion.- 2.3. Circumstantial Evidence Against a Quantum Size of 15,000 or More Transmitter Molecules.- 2.4. Validity of the Electrophysiological Method for Measuring Neurotransmitter Secretion.- 2.5.
  • Författare: Leslie Iversen
  • Format: Pocket/Paperback
  • ISBN: 9781468485165
  • Språk: Engelska
  • Antal sidor: 307
  • Utgivningsdatum: 2012-06-12
  • Förlag: Springer-Verlag New York Inc.