Biopharmaceutics and Pharmacokinetics

This book deals with the basics of the two disciplines of biopharmaceutics and pharmacokinetics. Different factors such as biological, physiochemical and formulation that influence the therapeutic efficacy of a drug are covered in biopharmaceutics. The absorption, distribution, metabolism and excretion of drugs are studied under this subject. Salient Features • Basics of biopharmaceutics and pharmacokinetics help to understand the various procedures and advances in drug design, product development, therapeutic drug monitoring, etc. • Pharmacokinetics covers the fundamentals of one compartment open model, multi-compartmental models. One compartment open model is presented in an elaborate manner to make the students familiar with various aspects of pharmacokinetics • Mathematical equations are developed using simple integration and differentiation methods • Practice problems are provided wherever necessary, and a question bank is included at the end of each chapter • Extreme care has been exercised to present the concepts in a simple way Second Edition includes • Application of principles in formulation development in industry for successful bioequivalence studies is included • One chapter on “In-vitro Dissolution Testing” is included to evaluate test formulations to chose right product for bioequivalence studies • A chapter on biostatistics with practice problems is included