Biophysics of Tissue Self-Organization in Morphogenesis

Biophysics of tissue self-organization in morphogenesis: The role of dynamics along the biointerface examines interactions between tissue and the extracellular matrix. This interdisciplinary book covers the fundamentals of cell self-rearrangement and the inter-relation between these biological mechanisms and physical mechanisms responsible for tissue self-organisation. It provides an introduction to tissue self-organisation in morphogenesis before exploring its physics from subcellular to supracellular levels. Modeling approaches to tissue self-organization are explored, followed by discussion of the application of engineering principles to solve biological and medical problems related to the tissue self-organisation. A range of tools, applications, and medical implications are also covered, including embryo development, wound healing, and cancerous diseases. The book closes with a look to future developments in the field. Biophysics of tissue self-organization in morphogenesis: The role of dynamics along the biointerface provides a detailed introduction to this topic, and is a valuable resource for researchers across the areas of cell biology, cell physiology, biophysics, developmental biology, tissue biomechanics, and pathophysiology.

• Describes biological mechanisms of cell self-rearrangement from subcellular to supracellular levels
• Explores mathematical modelling approaches of tissue self-organization
• Considers engineering principles to solve biological and medical problems related to tissue self-organisation
• Discusses tissue self-organisation within various in vivo and in vitro organoid systems