Blood-Infecting Protozoal Diseases

The present book describes the common human diseases caused by the blood infecting protozoans, diagnosis and treatment. This book compiles the latest literature on the genetic diversity, therapeutics, and drug resistance in protozoan parasites, with a focus on malaria parasites, Plasmodium falciparum, and P. vivex. It explores the association of parasite genetic makeup with drug resistance. The book covers the mechanisms of drug resistance, and its spread, and factors affecting drug resistance. The book facilitates research design and development of therapeutics against malarial parasites. The book is meant for post-graduate students of microbiology, parasitology, and medicine, as well as healthcare workers, medical practitioners, public health staff, and policymakers. Key Features Describes the recent updates on how the different protozoan parasites cause human diseases Includes the genomics and epidemiology of important protozoan parasites like Plasmodium, Trypanosoma, Leishmania, and Toxoplasma. Further, it covers the role of nanotechnology in diagnosis and treatment of the diseases. Covers the detection of drug resistance in vitro and in vivo and Insilco tools for functional genomics. Throws light on the aspect of copy number variation (CNV) as a part of the adaption strategy in parasites. Discusses the molecular basis of antimalarial drug resistance in Plasmodium vivax. Reviews the factors contributing to the spread of resistance in malaria parasites.