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This volume focuses on defining the unique attributes of using thezebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using thezebrafish model, the volume exploresoncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the mostprominent laboratories working in this field, which provides a unique perspective onzebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specificzebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver andpancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text onzebrafish and cancer, providing a much needed resource on the powerful attributes of thezebrafish model system.
- Format: Previously published in hardcover
- ISBN: 9783319808604
- Språk: Engelska
- Antal sidor: 552
- Utgivningsdatum: 2018-05-27
- Förlag: Springer International Publishing AG