Cancer Stem Cells and Signaling Pathways

Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression.

• Presents cancer stem characteristics and their signaling pathways
• Highlights the use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery
• Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers