Candida

Candida species are important human pathogens that are best known for causing opportunist infections in immunocompromised hosts (e.g. transplant patients, AIDS sufferers, cancer patients). Infections are difficult to treat and can be very serious. 30-40% of systemic infections result in death. The sequencing of the genome of C. albicans and those of several other medically-relevant Candida species has provided a major impetus for Candida comparative and functional genomic analyses. These have provided a fascinating insight into the molecular and cellular biology of these fungi, and these should pave the way for the development of more sensitive diagnostic strategies and novel antifungal therapies. In this timely book, international experts provide comprehensive and authoritative reviews of these important organisms. The topics covered include: genome dynamics of C. albicans; molecular, epidemiological, and population studies of C. albicans; the parasexual cycle in C. albicans; compara