Cellular Connectomics

The field of cellular connectomics is technically challenging and highly multi-disciplinary, creating need for a connectomics methods volume suitable for both researchers and students aiming to gain familiarity with the field. Cellular Connectomics offers just that: an accessible, practical and comprehensive introduction to the fundamental principles and practices of cellular connectomics. With the bulk of the volume written by two pioneers in the field, plus 3 chapters authored by opinion leaders offering future predictions, the volume offers readers both consistent voice/uniform structure and cutting edge insights. Focusing on "cellular" connectomics with the goal of reconstructing neuronal wiring diagrams at the level of single neurons/synapses, the volume provides a conceptual overview of the goals and challenges of this methodology.

• The first volume to offer a step-by-step introduction to cellular connectomics suitable for both researchers and students.
• Coverage includes: tissue preparation, sectioning and imaging techniques, approaches for data reconstruction, circuit analysis, and an explanation of successful connectomic reconstructions to date.
• Offers balanced discussion what does and does not work, as well as of the current debates about whether a connectomic era is going to replace decades of functional data collection.