Cholecystokinin

Professor Christine Feinle-Bisset has a PhD in Nutrition and GI Physiology from the University of Stuttgart-Hohenheim, Germany. After gaining research experience at the University of Sheffield, UK and the University of Zurich, Switzerland, she joined the University of Adelaide in 2000, where she is currently a Professorial Research Fellow and a lead investigator in the Centre of Research Excellence in Translating Nutritional Science to Good Health. Her research is clinical and relates to the impact of nutrients on appetite, GI motor and hormone function and perception, in health, obesity and functional dyspepsia. Her work has contributed significantly to current concepts of the role of gastrointestinal mechanisms, including gut hormones and gastrointestinal motor activity, in the regulation of energy intake in health and obesity, and symptom generation in functional dyspepsia. She has published more than 220 publications, with over 15,000 citations. Professor Jens F. Rehfeld has an MD from the University of Aarhus, and later DMSc and DSc in Clinical Biochemistry from the University of Copenhagen. He became professor in Medical Biochemistry at University of Aarhus in 1975, and of Clinical Biochemistry, University of Copenhagen, in 1981. He was also administrative head of the Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, until 2010.His main research theme is bioactive peptides (in particular gastrin, cholecystokinin, and insulin), their biosynthesis, methods for measurement, and clinical relevance. He has published approximately 1100 publications, including 650 original articles, 90 review articles, 55 textbook chapters, and 8 books, and has more than 43,000 citations.

• Part I - History1. Milestones in the history of cholecystokininJens F. Rehfeld, Christine Feinle-Bisset Part II - Biology of cholecystokinin2. Evolutionarily conserved roles of cholecystokinin signalingDick Nässel, Shunfan Wu 3. The biogenesis and cell-specific expression of cholecystokinin peptidesJens F. Rehfeld, Christine Feinle-Bisset 4. Cholecystokinin in intestinal and extraintestinal endocrine cellsMarta Santoz Hernandez, Frank Reimann, Fiona M. Gribble 5. Cholecystokinin in the central and peripheral nervous systemTomas Hökfelt, Swapnali Barde, Wen Zhong, Jufang He 6. Cholecystokinin 1 and cholecystokinin 2 receptorsLaurence J Miller 7. The relationship between cholecystokinin and gastrinJens F. Rehfeld Part III - Physiology of cholecystokinin8. Intestinal cholecystokinin secretionRashmi Chandra, Rodger A. Liddle 9. Cholecystokinin and the gut-brain axisKirsteen Browning, Amanda Page Cholecystokinin and the gallbladderAdrian A. M. Masclee, Gwen M. C. Masclee 11. Cholecystokinin and the exocrine pancreasJohn A. Williams 12. Islet effects of cholecystokinin and exploitation in diabetesNeil Tanday, Nigel Irwin, Peter Flatt 13. Cholecystokinin and gastrointestinal motor functionJavad Anjom Shoae, Michael Horowitz, Christine Feinle-Bisset 14. Effect of cholecystokinin on food intake and appetiteFrank A. Duca 15. Cholecystokinin, nutrient preference and taste aversionJo E. Lewis, Fiona M. Gribble, Frank Reimann 16. Cholecystokinin in peripheral and central cardiovascular controlTony J. M. Verberne, Bashair M. Mussa 17. Cholecystokinin in cardiac myocytesJens P. Goetze, Jens F. Rehfeld Part IV – Methods used for cholecystokinin research18. Measurement of cholecystokinin in biological fluidsJens F. Rehfeld, Jens P. Goetze 19. Cholecystokinin knockout mice: peripheral and central phenotypesChunmin C. Lo, Dennis D. Black, Patrick Tso Part V - cholecystokinin in disease20. Cholecystokinin in obesity and other disorders of eatingKimberly R. Smith, Tim H. Moran 21. Cholecystokinin in tumorsJens F. Rehfeld 22. Cholecystokinin and panic disorderJacques Bradwejn, Diana Koszycki 23. Cholecystokinin and the immune systemJohn J. Worthington 24. Cholecystokinin in nociception and painNesia A. Zurek, Sascha R. A. Alles Part VI – cholecystokinin -based novel therapeutic approaches25. Potential therapeutics targeting cholecystokinin 1 receptorsLaurence J. Miller Part VII - Conclusion26. Reflections on cholecystokinin research: past, present and futureJens F. Rehfeld, Christine Feinle-Bisset