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584 sidor
2016

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. Guides researchers as to what drug safety experiments are both practical and useful Covers a variety of key topics safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and omics tools Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

Författare: Yvonne Will, J Eric McDuffie, Andrew J Olaharski, Brandon D Jeffy
Illustratör: illustrations
Format: Inbunden
ISBN: 9781119053330
Språk: Engelska
Antal sidor: 584
Utgivningsdatum: 2016-07-01
Förlag: John Wiley & Sons Inc