Drug-excipient-shell interactions using thermoplastic capsules 1

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Drug-excipient-shell interactions using thermoplastic capsules

Zdravka Misic • Martin Kuentz • Georgios Imanidis

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192 sidor
2019

This book introduced novel starch-based thermoplastic capsules (S-PVA-Cs) and demonstrated their advantage over SGCs with respect to hydrophilic lipid-based formulations. Release studies in biorelevant media revealed differences in how formulations hydrated and interacted with the shell material. Drug-excipient-shell interactions were observed in various capsule types (SGCs, S-PVA-Cs, and VegaGels) at different levels of biopharmaceutical in vitro testing. A better mechanistic understanding was attained that may guide future development of soft capsule products.

Författare: Zdravka Misic, Martin Kuentz, Georgios Imanidis
Format: Pocket/Paperback
ISBN: 9786202007146
Språk: Engelska
Antal sidor: 192
Utgivningsdatum: 2019-09-23
Förlag: LAP Lambert Academic Publishing