bokomslag Epigenetic Cancer Therapy
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Epigenetic Cancer Therapy

Steven Gray

Inbunden

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  • 748 sidor
  • 2015

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.

The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).

The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.




  • Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlas
  • Discusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applications
  • Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs
  • Författare: Steven Gray
  • Illustratör: 50
  • Format: Inbunden
  • ISBN: 9780128002063
  • Språk: Engelska
  • Antal sidor: 748
  • Utgivningsdatum: 2015-08-24
  • Förlag: Academic Press