Examining Glucagon-Like Peptide-1 Receptor (Glp-1r) Agonists for Central Nervous System Disorders: Proceedings of a Workshop
National Academies Of Sciences Engineeri • Health And Medicine Division • Board On Health Sciences Policy
Häftad
Glucagon-like peptide-1 receptor (GLP-1R) agonists, originally developed for type 2 diabetes patients and popularized by their ability to rapidly reduce body weight in patients with obesity, have recently received a lot of national attention. Repurposing GLP-1R agonists to treat some central nervous disorders is promising, but comparatively understudied. At a September 2024 workshop, the National Academies Forum on Neuroscience and Nervous System Disorders reviewed the current knowledge and research gaps about the mechanisms of action of GLP-1R agonists in the brain, and the evidence of their clinical efficacy for eating disorders, neurodegenerative diseases, substance use disorders, and pain.
- Format: Häftad
- ISBN: 9780309735056
- Språk: Engelska
- Antal sidor: 118
- Utgivningsdatum: 2025-11-01
- Förlag: National Academies Press