Fundamentals of Genetic Epidemiology

This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease aetiology. The authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations. In describing the fundamental research strategies of genetic epidemiology, they emphasize methods of studying familial aggregation such as linkage and segregation analysis.