Fundamentals of Redox Biology

Fundamentals of Redox Biology provides a complete introduction to the cellular redox systems, exploring their regulation, physiological role and significance to human diseases. The book begins with a historical overview before exploring the fundamental characteristics and functions of free radicals and reactive oxygen species. Their role in redox signaling and epigenetic regulation are covered, as well as the impact of antioxidants on redox homeostasis. Additionally, the book explores how ROS can lead to oxidative stress and various disease states, including cancer, cardiovascular and neurological disorders, while also considering the role of mitochondrial ROS in the immune response against various infections.

Biology of cellular redox systems has now become an integral part of many disciplines across the life sciences. This book provides a foundational overview of the topic which will be useful to those in the field of biochemistry, cell biology, molecular biology, immunology, and related areas.

• Examines the role of free radicals and reactive species (ROS) in human health and disease
• Explores redox biology in the context of humans, plants, Zebrafish and Drosophila
• Considers tools and techniques for the detection and estimation of cellular ROS
• Looks at the role of ROS in genetic and epigenetic regulations
• Features learning objectives and end-of-chapter problems to aid understanding