Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America

In this issue ofHematology/Oncology Clinics,guesteditorsDrs.Sung-Yun Pai andNiraliN. Shahbringtheirconsiderable expertise to the topic ofGene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics suchasCAR T-cell therapy: current status; engineered T cells;NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B;primary immunodeficiencies;and more. Contains14relevant, practice-oriented topicsincludingthe evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids;regulatory aspects of gene therapy; and more. Provides in-depthclinical reviews ongene-based therapies for pediatric blood diseases,offeringactionable insights for clinical practice. Presents thelatest information on this timely, focused topicunder the leadership of experienced editors in the field.Authors synthesize and distill the latest research and practice guidelines to createclinically significant,topic-based reviews.