Gluten-Related Disorders: Diagnostic Approaches, Treatment Pathways and Future Perspectives

Gluten is a group of proteins including glutelins and prolamins, which exists with starch in the endosperm of several cereal grains. Gluten-related disorders refer to those disorders caused due to gluten. It encompasses various diseases such as gluten ataxia, celiac disease, wheat allergy, non-celiac gluten sensitivity and dermatitis herpetiformis. Such disorders are classified as allergic diseases, autoimmune disorders and non-autoimmune disorders. There are various symptoms of gluten sensitivity such as diarrhea, abdominal discomfort or pain, bloating, and constipation. Individuals having celiac disease can go through serological testing for IgA anti-tissue transglutaminase antibodies and anti-endomysial antibodies where IgA-level is high. If the IgA is low, the person may undergo IgG antibodies testing. If there is a sign of positive serological indication, a duodenal biopsy is required to confirm active celiac disease. The treatment of this disease is only possible by following a lifelong gluten-free diet. This book contains some path-breaking studies on gluten-related disorders. It presents researches and studies performed by experts on the diagnostic approaches, treatment pathways and future perspectives related to these disorders. This book is appropriate for students seeking detailed information on gluten-related disorders as well as for experts.