Handbook of Translational Transcriptomics

Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview to the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussion of choosing the correct approach based on the research needed, it also highlighting the pros and cons of each approach. Following this it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, expression arrays, and gene expression, providing detailed. It then delves into data analysis and offers recommendations, guidelines, and approaches related to data interpretation. The book also considers the translation of transcriptomics to clinical application and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research. Handbook of Translational Transcriptomics is a detailed reference that provides a complete view of transcriptomics, ranging from methods to handling data and medical applications.

• Features practical guidance and protocols for researchers to replicate transcriptomic methods and techniques, including wet lab techniques
• Includes useful information on analyzing and interpreting transcriptomic data
• Offers a detailed introduction into translational transcriptomics, exploring both coding and non-coding RNAs including microRNA.
• Investigates clinical implications of transcriptomics and applications to treating disease
• Considers some experimental and bioinformatic techniques in the field of transcriptomics, as well as more established approaches