Histocompatibility Testing

Successful transplantation depends on the minimization of immunological differences between the donor and recipient tissues. These differences are based on polymorphisms of the human major histocompatibility complex and play a major role in determining the acceptance or rejection of allografts during transplantation.

Histocompatibility Testing: A Practical Approach describes methods for the investigation of Mhc at the gene and protein levels and their application to the clinical transplanation of human organs and bone marrow. There is currently no other text available covering up-to-date serological and molecular techniques in this area of immunogenetics, despite their importance to fundamental research, clinical practice, and forensic medicine. This book will therefore be of great interest to workers in many subject areas, irrespective of whether they are in established laboratories or are entering this field for the first time.