Molecular Toxicology Protocols

The text brings together a series of works, each applying the most commonly used methods to elucidate specific molecular aspects of toxicology. Molecular Toxicology Protocols is divided into four parts, each describing the application of methods to study a specific aspect of toxicology. Part I describes applications and methods to analyze products of interactions between cellular macromolecules, such as DNA and proteins, and chemical and physical agents. Part II contains chapters describing the applications of methods to assess genotoxicity and characterize genetic alterations induced by both in vitro systems and in vivo. Part III includes methods for the analysis of cytotoxicity caused by the induction of apoptosis. Finally in Part IV, the editors describe methods for the analysis of individual variation in biotransformation and in DNA repair capacity. A well-rounded look into the latest findings in this field is provided for molecular biologists, molecular toxicologists as well as individuals interested in applying molecular methods to clinical applications.