Natural and Artificial Metalloenzymes

The subject of bioinorganic chemistry is one of the most intellectually attractive and experimentally demanding frontiers in modern chemical science. The problems of this interdisciplinary field are some of the most fascinating at the interface of chemistry, biology, and medicine. This volume brings together world-leaders in the field of bioinorganic chemistry, interlinked with spectroscopic and computational/theoretical physical chemists, to discuss current mechanistic insights into the function of many metalloenzymes, as well as small molecule activation, the synthetic analogue approach to metalloproteins/enzymes, artificial enzymes, the therapeutic use of metal-ligand complexes and the methodologies (both experimental and theoretical) in this area of research. In this volume, the topics covered include: Small molecule activation and synthetic analogues Techniques for studying the kinetics and thermodynamics of metal-ligand exchange reactions Electron transfer, spectroscopy and theory Natural and artificial enzymes and medicinal aspects