Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimers Disease

The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO. Treatments and potential cures for Alzheimers have been researched for a long time now. Conventional drugs, while providing symptomatic relief, have often fallen short of halting the relentless progression of this neurodegenerative disorder. This new two-volume set, Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimers Disease, 2-volume set, represents a collective effort to delve into the potential of natures pharmacopeia in our battle against Alzheimers disease. The editors posit that essential insights into the intricacies of the disease are the foundation for subsequent discussions on potential therapeutic interventions. Volume 1: Targeting Key Pathological Pathways first lays the foundation by unveiling the underlying pathological, biochemical, molecular, and genetic aspects of Alzheimers disease. These chapters provide essential insights into the intricacies of the disease and serve as a springboard for the subsequent discussions on potential therapeutic interventions. Chapters cover pathophysiology and diagnosis, the connection of gut microbiome and Alzheimers disease, drug-induced Alzheimers disease, and more. The volume then goes on to shine a spotlight on the vast potential of nutraceuticals in managing Alzheimers disease. It explores a plethora of medicinal plants and their secondary metabolites that show promise in treating this devastating condition. From preclinical findings to clinical studies, the chapters present a wealth of knowledge on memory improvement effects and the mechanisms underlying the actions of these neuronutraceuticals. Covered are the role of diet, micronutrients, and macronutrients in managing Alzheimers disease; Medhya Rasayana (medicinal plants described in the Indian system of medicine that are said to improve memory and intellect); nootropics (also known as drug cognitive enhancers that help to improve memory, increase mental alertness and concentration as well as boost energy levels and wakefulness); and other ethnopharmacological approaches for dementia. Together, these volumes not only reflect the current state of knowledge but also pave the way for future exploration in the field. Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimers Disease will enlighten readers, whether seasoned researchers, practitioners, or advanced students, with a wealth of scientific knowledge gained through the cutting-edge research and in-depth exploration of the therapeutic potential of natures offerings and shall contribute to the ongoing efforts in managing dementia and cognitive disorders.