New Rapid-acting Antidepressants

This book discusses new candidates for rapid-acting antidepressants,such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3antagonists and AMPA receptor agonists. There are serious limitationsto currently available antidepressants, such as delayed onset and lowrates of efficacy. The discovery that a single dose of ketamine, anNMDAR antagonist, can produce rapid antidepressant effects that aresustained has led to new research in this area. In this volume, avariety of novel pharmaceutical treatments are examined. This volumewould be useful to both researchers and clinicians who work in the fieldof pharmacology, specifically CNS drug treatments.