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This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.
- Format: Inbunden
- ISBN: 9783036530833
- Språk: Engelska
- Antal sidor: 114
- Utgivningsdatum: 2022-01-31
- Förlag: Mdpi AG