Pharmaceutical Microemulsions for Parenteral Delivery

Parenteral delivery of hydrophobic drugs is a challenging task. Constant research on exploiting newer approaches to make the delivery of pharmaceuticals by nondigestive tracts effective yet safe and cost effective continues. Microemulsion is one such approach that has been employed in recent years for parenteral delivery. This new book, Pharmaceutical Microemulsions for Parenteral Delivery: From Bench to Bedside, provides systematic information regarding the preformulation of drugs, formulation using quality by design (QbD) principles, and characterization of parenteral microemulsions for drug delivery. The book explores specific aspects of microemulsions such as the role of surfactants and cosurfactants in formulation, clinical aspects of parenteral microemulsion, regulatory perspectives and patents, as well as future challenges in this field of research. It covers the QbD paradigm for formulation optimizations using different software systems. It also covers the regulatory expectations and safety issues at various stages of the development pharmaceutical microemulsions. The book details large-scale manufacturing aspects as well as presents an overview of the patent landscape for parenteral use of microemulsions. Serving as a reference guide for the development of parenteral microemulsion-based formulations, this volume will be an important source of know-how for investigators wishing to work in this area, be it from academia or industry.