Del 71 - Progress in Drug Research

Pharmacological Assays of Plant-Based Natural Products

Häftad, Engelska, 2018

Av Thangaraj Parimelazhagan

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This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.

Produktinformation

Utgivningsdatum2018-03-31
Mått155 x 235 x 12 mm
Vikt318 g
FormatHäftad
SpråkEngelska
SerieProgress in Drug Research
Antal sidor188
FörlagSpringer International Publishing AG
ISBN9783319800202

Tillhör följande kategorier

Analytisk kemi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Farmakologi inom Medicin
Växtböcker inom Djur och natur
Botanik inom Naturvetenskap och teknik

Parimelazhagan Thangaraj is aProfessor in the Department of Botany, Bharathiar University, Coimbatore – 641046, India. His field of specialization is Bioprospecting of Medicinal Plants. He is currently engaged in compilation and documentation on available knowledge onvaluable plant resources to prove their utility scientifically through detailedphytochemical, biological and pharmacological investigations.

1. Extraction of plant material.- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays.- 4. In vivo antioxidant assays.- 5. Quantification assays.- 6. Anti-nutritional factors.- 7. Anti-inflammatory activity.- 8. Antipyretic activity.- 9. Inflammation bowel disease.- 10. Anti-arthritic activity.- 11. Evaluation of analgesic potential.- 12. Anti-diarrhoeal activity.- 13. Anti-ulcer activity.- 14. In vitro anti-diabetic activity.- 15. In vivo anti-diabetic activity.- 16. Hepatoprotective property.- 17. Antitumor activity.- 18. In vivo wound healing studies.- 19. Determination of cytotoxicity.- 20. Evaluation of bioavailability.- 21. Molecular identification by DNA barcoding.- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.