Prenatal Diagnosis of Fetal Osteopathologies

Dr. Aniello Di Meglio is a specialist in Obstetrics and Gynecology. He has been using ultrasound technology since graduating, starting with the A-mode technique and moving on to the most modern technological innovations. He has always been attentive to technological progress and believes that the true improvement of medical art comes from physicists, chemists, and engineers. In order to improve their positive impact on patients, medical doctors have to be attentive and ready to receive all innovations. Dr. Di Meglio believes that the primary task of medical doctors is to communicate and disseminate their knowledge to students and young doctors, and this is the aim behind each of the many didactic activities Dr. Di Meglio is involved in.

• Classification of osteodysplasias and study protocol.- Classification of osteodysplasias and dysmorphic syndromes with skeletal involvement.- Cranial anomalies.- Congenital deformities of the spine.- Deformities of the thoracic cage and pelvis.- Ectromelia.- Congenital deformities of the upper limb.- Congenital deformities of the lower limb.- Exogenous causes of osteopathy.- Osteodysplasias.- Lethal micromelic type osteodysplasias.- Rhizomelic dwarfism dysplasias.- Mesomelic dwarfism.- Mesoacromelic dysplasias.- Acromelic dysplasias.- Dysplasia with severe proximal-distal micromelia.- Osteodysplasias with isolated or concurrent involvement of epiphyses, metaphyses, and vertebral bodies.- Congenital sclerosing, hyperostotic, and dysmodelling osteopathies.- Rarefying and hypostotic osteopathies.- Osteopathies from anarchic tissue development.- Idiopathic osteolysis.- Chromosomal aberrations.- Dismorphic syndromes with skeletal anomalies.- Lethal or sublethal evolving syndromes.- Dismorphic syndromes with craniofacial anomalies.- Dismorphic syndromes with anomalies of the skull and extremities.- Dismorphic syndromes with anomalies of the oral cavity and extremities.- Dismorphic syndromes with predominant involvement of the limb skeleton.- Dismorphic syndromes with predominant involvement of the trunk.- Dismorphic syndromes with bone overgrowth.- Dismorphic syndromes with dolichostenomelia.- Dismorphic syndromes with joint stiffness.- Dismorphic syndromes with prenatal dwarfism and skeletal anomalies.- Dismorphic syndromes with cerebral and skeletal anomalies.- Dismorphic syndromes with ocular and skeletal anomalies.- Dismorphic syndromes with cardiac and skeletal anomalies.- Dismorphic syndromes with pulmonary and skeletal anomalies.- Dismorphic syndromes with renal and skeletal anomalies.- Dismorphic syndromes with genital and skeletal anomalies.- Dismorphic syndromes with cutaneous and skeletal anomalies.- Dismorphic syndromes with pterygium and skeletal malformations.- Dismorphic syndromes with amartomatous and skeletal anomalies.- Syndromes that combine progeria and skeletal malformations.- Syndromes that combine anemia or thrombocytopenia with skeletal defects.- Skeletal anomalies and twin pregnancies.- Hereditary muscle-spinal malformations.- Skeletal syndromes resulting from metabolic anomalies.- Images of normal bone.- Biometry.- Prenatal genetic counseling.- Genetic investigations (the synergy between obstetrician and geneticist in the prenatal diagnosis of congenital defects).- Legal aspects in the ultrasound diagnosis of fetal osteopathology.- Doubt: recognition or diagnostic accuracy?- Reporting.- Conclusions.- Glossary.- Analytical index.