bokomslag Role of Capsaicin in Oxidative Stress and Cancer
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Role of Capsaicin in Oxidative Stress and Cancer

Sanjay K Srivastava

Inbunden

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  • 178 sidor
  • 2013
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
  • Författare: Sanjay K Srivastava
  • Illustratör: 3 schwarz-weiße Tabellen 18 schwarz-weiße und 7 farbige Abbildungen
  • Format: Inbunden
  • ISBN: 9789400763166
  • Språk: Engelska
  • Antal sidor: 178
  • Utgivningsdatum: 2013-05-07
  • Förlag: Springer