Role of Gut Microbiome in Neurodegenerative Disorders

Gut microbiota refers to the symbiotic microorganisms like bacteria, archaea, viruses, and fungi present in the human gut. These diverse groups of microorganisms play multiple roles in humans, even the Central Nervous System. Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book reviews the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), Multiple sclerosis (MS). Some chapters will discuss the effects of gut derived particles in various parts of brain and the targeting pathways leading to protein deposition in brain.

• Reviews the pathology and pathophysiology of gut derived neuropeptides in neurodegenerative disorders
• Discusses mechanism of gut derivatives on immune system
• Presents possible therapy mechanism using gut microbiome