Kropp & själ
Signal Transduction in Leukocytes
Pramod M Lad • John S Kaptein • Ching-Kow Lin
Inbunden
4679:-
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Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers. Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.
- Format: Inbunden
- ISBN: 9780849366949
- Språk: Engelska
- Antal sidor: 400
- Utgivningsdatum: 1995-11-01
- Förlag: CRC Press Inc