Single-particle Cryo-EM of Biological Macromolecules
Robert M Glaeser • Eva Nogales • Wah Chiu
Inbunden
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This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. It is especially well suited for larger complexes and molecular machines. This book, provides a comprehensive, accessible and authoritative introduction to the field. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results.
Key features
- Written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM
- Provides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-article cryo-EM
- Covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results
- Authors of individual sections of this book have been recruited from among the most authoritative leaders in each topic
- Format: Inbunden
- ISBN: 9780750330374
- Språk: Engelska
- Antal sidor: 318
- Utgivningsdatum: 2021-05-19
- Förlag: Institute of Physics Publishing