Study of Lipid Peroxidation in Pre-eclampsia

The present study was carried out in patients with pre-eclampsia (Group I, n= 25), and also in age and parity matched normotensive pregnant women (Group IB n=25) and normal non-pregnant women (Group IA, n = 25) admitted in obstetrics and Gynaecology wards of the Medical College and Hospital between October 1993 to March 1994. The observations made in the three groups were analysed. The following results were obtained: All the pre-eclamptic women (Group II) had proteinuria. Five women had complaints of headache, nausea, vomiting and syncope. Five patients had edema over the face and abdomen in addition to feet. Mean values of systolic and diastolic BP recorded in preeclamptic women were 149.6 102.6 mmHg and in normotensive pregnant being 111.28 mmHg and 66.24 mmHg respectively. In pre-eclamptic women uric acid level was increased (mean 7.68 mg%) than normotensive pregnant (mean 5.0 mg%). In normotensive pregnant ( group I B) mean birth weight was 2500g and gestation age was 38.2 weeks (range 37 to 40 weeks).