The Chemistry of Hyperpolarized Magnetic Resonance Probes

The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included.

• Helps readers understand the structural features that determine the properties of HP-probes, such as chemical shift and relaxation times
• Aids readers in selecting stable isotope labeled probes for hyperpolarized NMR/MRI applications
• Teachers readers how to use the most appropriate synthetic methodology for the labeled probes
• Covers how to find the most suitable polarization technique (DNP, PHIP etc.) for the probe