Kommande
bokomslag The Extracellular Matrix in Genetic Skeletal Disorders
Kropp & själ

The Extracellular Matrix in Genetic Skeletal Disorders

Antonio Rossi Frank Zaucke

Inbunden

4449:-

Funktionen begränsas av dina webbläsarinställningar (t.ex. privat läge).

  • 410 sidor
  • 2025
This book explores how defects in extracellular matrix (ECM) proteins, their post-translational modifications, and intracellular trafficking impact cartilage and bone integrity. It underscores the ECM's role in providing structural support, establishing morphogenetic gradients, and interacting with cell surface receptors in musculoskeletal tissues. The book delves into the structure and biology of the ECM in the skeleton, discussing skeletal disorders caused by mutations in genes associated with ECM proteins, synthesis, turnover, and signal transduction. Authored by experts who have made significant discoveries in the molecular mechanisms of skeletal disorders and are developing therapeutic strategies, this book is an invaluable research for both scientists and clinicians seeking a comprehensive understanding of this growing and exciting field. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
  • Författare: Antonio Rossi, Frank Zaucke
  • Format: Inbunden
  • ISBN: 9783031708343
  • Språk: Engelska
  • Antal sidor: 410
  • Utgivningsdatum: 2025-01-26
  • Förlag: Springer International Publishing AG