The Role of the Mitochondria in Neural Degeneration

The Role of the Mitochondria in Neural Degeneration, a new volume in Elsevier's Hot Topics in Physiology series, examines the significance of mitochondria and their impairment in the development of neurodegenerative conditions. The book opens with an introduction to mitochondria and their significance in neuronal function before exploring the cause and effect of mitochondrial impairment. Following chapters then cover a range of aspects, including mitochondrial dynamics in neurodegenerative diseases, mitophagy, and autophagy in neuronal degeneration and mtDNA integrity. Intercellular connection damage and the effect this can have on cellular function is also investigated. Finally, the book closes with a section on therapeutic interventions for targeting mitochondria in the treatment of human diseases. This series is published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for cell biologists, investigators in mitochondrial biology, and researchers working with neurodegenerative diseases.

• Examines the role of mitochondria in neuronal function and survival
• Presents the latest findings on mitochondrial dysfunction, along with dynamics in neurodegenerative diseases
• Considers the impact of mitochondrial intercellular connections on neuronal health
• Discusses potential therapeutic options and the latest advances in mitochondrial medicine for the treatment of mitochondrial impairment