bokomslag Thymic Development and Selection of T Lymphocytes
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Thymic Development and Selection of T Lymphocytes

Thomas Boehm Yousuke Takahama

Inbunden

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Andra format:

  • 132 sidor
  • 2013
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
  • Författare: Thomas Boehm, Yousuke Takahama
  • Illustratör: 130 p
  • Format: Inbunden
  • ISBN: 9783642402517
  • Språk: Engelska
  • Antal sidor: 132
  • Utgivningsdatum: 2013-11-19
  • Förlag: Springer-Verlag Berlin and Heidelberg GmbH & Co. K