bokomslag Ubiquitin-proteasome Proteolytic System, The: From Classical Biochemistry To Human Diseases
Kropp & själ

Ubiquitin-proteasome Proteolytic System, The: From Classical Biochemistry To Human Diseases

Aaron J Ciechanover Maria Grazia Masucci

Inbunden

1569:-

Funktionen begränsas av dina webbläsarinställningar (t.ex. privat läge).

Tillfälligt slut online – klicka på "Bevaka" för att få ett mejl så fort varan går att köpa igen.

  • 240 sidor
  • 2002
Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory.This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes.
  • Författare: Aaron J Ciechanover, Maria Grazia Masucci
  • Format: Inbunden
  • ISBN: 9789812381002
  • Språk: Engelska
  • Antal sidor: 240
  • Utgivningsdatum: 2002-11-01
  • Förlag: World Scientific Publishing Co Pte Ltd