Vaccines

Generations of new vaccines such as DNA-based vaccines, multipeptide, lipopeptide, molecular, cellular and replicon-based vaccines are currently being developed to help combat viral, bacterial, and parasitic infections, and non-infectious diseases including cancer, autoimmune diseases, allergies, neurodegenerative and metabolic diseases. In this book internationally acclaimed authors review current strategies and approaches in vaccine development. Topics covered include the immunological basis for rational design of new vaccines, targeting the innate immune system, mucosal immunity, vaccine safety, and vaccine vector technology. Several chapters are devoted to the development of vaccines to combat specific diseases such as tuberculosis, nosocomal infections, rotaviruses, human papillomavirus, cancer, and allergies.