Moving Toward Nonanimal Approaches in Medical Research and Testing

Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodology, funding opportunities for nonanimal studies, advocacy for regulatory change regarding approval of human therapeutics through nonanimal studies, and how to overcome the publication bias against nonanimal studies. This book is presented in three parts: 1) historical, ethical, legislative, regulatory, and scientific contexts to animal-based research and testing, 2) the latest advances in nonanimal tools and methods for research and testing of human therapeutics, and 3) achieving a practical shift toward nonanimal-based research and testing requirements. This book, primarily directed to researchers in biomedicine and human medical therapeutics, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods. Clinicians who wish to understand the methods and reliability of nonanimal versus animal-tested therapeutics as well as advocacy groups seeking to present up-to-date understanding of the reliability of animal versus nonanimal testing methods will also find significant value in this text. Finally, regulators and those involved in regulatory review and legislative oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

• Presents an overview of historical, ethical, and regulatory issues regarding animal and nonanimal research
• Delivers up-to-date information on the latest in nonanimal experimental advances and methods
• Provides practical guidance about overcoming funding, publication, and other hurdles for nonanimal research
• Discusses practical approaches to advancing nonanimal research and subjugating publication bias to animal research